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Welcome to the PPI-hotspotID prediction server.

Your job has finished and the results locating the PPI-hotspotID residues are available as results.txt.
They are listed here too for chain A:
PPI-hotspotID: Ala4, Met9, Leu16, Ala17, Ala19, Ala20, Gly23, Leu31, Gly35, Leu37, Ala40, Tyr44, Gly45, Ile49, Met54, Gly55, Ala60, Leu62, Leu63, Leu64, Gly67, Ala68, Pro70, Ala73, Arg80, Asp84, Ala85, Ala86, Gly89, Asp92, Leu97, Gly101, Ala102, Leu104, Gly111, Leu113, Ala118, Gly122, Tyr129, Leu130, Ala134, Ala148, Glu149, Asp156.

The input pdb file is here, the conservation grades can be found here

The image shows the backbone of your protein structure, the predicted PPI-hotspotID results are depicted in red.

If the image to the left is missing, then you probably need to turn on Javascript for your browser and restart your browser. We use the JSmol Javascript version of Jmol to produde these images.
To get information on a residue hover the mouse over that residue for ~1 second,
To rotate use left-click,
To translate use ctrl & right-click and
To zoom use the mouse wheel.


Right-clicking on the image will bring up the Jmol menu and also allows the console to be displayed for additional selections to be made.


Plot of PPI-hotspotID residues vs. residue numner, residues predicted to be PPI-hotspotID are scored as 1, those not are scored as 0.5.

Residues plot

PPI-hotspotID is hosted at The Institute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan.